Ethanol Alternatives – Chinese Hamster Ovary (CHO) Cells

“Fuels to Pharma: Versatile TITAN Adapts: Unveiling the Potential of Chinese Hamster Ovary (CHO) Cells”

The introduction of TITAN Renewable Hydrogen Producers Gas + Microbial Fermentation Platform heralds a transformative shift in the bioprocessing sector, poised to revolutionise traditional manufacturing paradigms. By harnessing renewable energy sources such as hydrogen from its cutting-edge gasification process, TITAN offers a sustainable alternative to conventional methods. This not only mitigates environmental impact but also drives down operational costs, aligning with the evolving economic dynamics.

TITAN’s advanced fermentation capabilities further bolster its transformative potential. With its ability to accommodate diverse microbial cultures, including the crucial CHO cells, TITAN provides a versatile platform adaptable to the dynamic demands of bioprocessing. This flexibility empowers facilities to optimise their manufacturing processes, enhance protein yields, and ultimately elevate production efficiency to unprecedented levels.

In essence, TITAN Renewable Hydrogen Producers Gas + Microbial Fermentation Platform emerges as a catalyst for economic and technological advancement in bioprocessing. By redefining industry standards and introducing sustainable practices, TITAN paves the way for a more resilient and efficient future in biotech manufacturing.

The global market potential for Chinese hamster ovary cells (CHO) reached approximately USD 243.61 million in 2022 and is forecasted to increase to about USD 379.51 million by 2030, reflecting a compound annual growth rate (CAGR) of approximately 5.70% from 2023 to 2030.

Syngas Project Pioneering Solutions for a Healthier Future

 Mr Hyde

We asked AI no. 5: “What Alternative Markets?”

Could the TITAN Platform’s versatility confront insulin injustice by increasing availability and lowering cost?

As we finalise the design for TITAN’s cutting-edge ethanol production, our focus extends beyond conventional energy solutions towards pioneering advancements in healthcare. With the potential to revolutionise the production of insulin, TITAN embodies a vision of innovation that transcends traditional boundaries.

The decision to explore insulin production stems from the alarming rise of diabetes, particularly in the United States and Europe. Diabetes has become an epidemic, with its prevalence mirroring the exponential growth of obesity rates. In the U.S. alone, nearly 10 per cent of the population suffers from diabetes, while another 12 per cent are at high risk due to factors like obesity.

This epidemic imposes significant financial and human costs, with healthcare expenditures related to diabetes reaching billions annually. Moreover, poorly managed diabetes leads to severe complications such as kidney disease, heart disease, and blindness, further exacerbating the crisis.

How Dark Hydrogen became the New Green

The “new green hydrogen” is “dark bio-hydrogen”, so called after the dark fermentation bio-manufacturing process which creates it green because its manufacture and existence are entirely organic, renewable and waterless. 

We choose to go to the moon JFK 1962 Moonshot Speech
60 years on from JFK moonshot speech

One small step ahead of carbon capture and storage CCS replacing it instead with capture and transformation CCT, thus taking the capture and recycling of waste carbon to the next level is a giant leap for mankind. 60 years on from JFK’s moonshot speech and on its anniversary Joe Biden announced the cure for cancer is the new moonshot and its through bio-technology transformation that will get us there.

TITAN and ASMARA incorporate two technologies on one platform, waste to hydrogen producer gas + microbial fermentation to manufacture fuel, chemical and material products. CCT is a well-proven process for recycling both the carbon at the smoke stack, in the waste we produce and in the waste we throw away as it is for the carbon we have already produced. We are presented with a truly value-added proposition because recycling the carbon we already have obviates the need to dig up more carbon. Through converting solid waste into producer’s gas and CCT emission technology to recycle carbon in the producer’s gas through, microbial fermentation, we can reproduce all of the products we currently manufacture from oil and gas, where the likes of transport fuels, plastics and fertilisers are produced with far less environmental impact. In manufacturing, this great array of products as an added bonus, large quantities of waterless green hydrogen is recovered as a byproduct.        

Dark bio-hydrogen presents a disruptive edge to the idea of hydrogen as an energy carrier because it does not burden our ever-depleting water supply, instead, hydrogen is recovered from changing the state of organic feedstock through a proprietary, bio-manufacturing process where carbon-rich waste biomass or bio-waste is transformed from solid state to a gaseous state and as a feedstock for fermentation.  


TITAN next generation ethanol and the decarbonisation of our skies

Revised: Steve Walker 16.10.2023


Ethanol is poised to be a pivotal player in our future energy landscape, especially in the effort to decarbonize current transportation. This significance is underscored by EU directives mandating increased ethanol blending with petrol and diesel at fuel stations. Simultaneously, global directives emphasize the pivotal role of second-generation ethanol (2G EtOH) in reducing aviation emissions. Following the EU’s inclusion of preferential subsidies to second-generation ethanol production and utilisation in 2021, 2022, and again in 2023, highlighting the imperative to hasten the shift to sustainable fuels, the role of platforms like TITAN in converting forest waste into 2G EtOH gains added importance. This commitment aligns seamlessly with the worldwide emphasis on diminishing carbon emissions and fostering cleaner alternatives.

In April 2023, the European Union approved the ReFuelEU Aviation proposal which imposes blending mandates on synthetic fuels for aviation, increasing from 0.7% in 2030 to 28% in 2050.

TITAN, an innovative platform converting forest waste into 2G EtOH, distinguishes itself with its commitment to sourcing renewable, non-food chain materials. This guarantees that the energy used in the production process is entirely divorced from coal or oil, presenting substantial environmental advantages. As the 2G EtOH market matures, TITAN’s platform technology not only converts waste carbon into advanced fuels, chemicals, and materials but also exemplifies a sustainable and circular approach.

The Hydrogen Producer Gas to Microbial Fermentation process employed by TITAN is transformative, safely and cleanly replacing conventional oil and gas products. With an impressively minimal carbon footprint and almost negligible refinery carbon emissions, TITAN’s 2G EtOH is crafted from 100% renewable local forest waste, conventionally destined for landfills.

ASMARA Hydrogen Producers Gas to Microbial Fermentation the key to upcycling thermoplastics

Warsaw 7 July 2022

The SOLIDEA Groups ASMARA platform converts all waste plastics [except PVC] into new biodegradable plastics. So-called PHA-derived plastics have the same characteristics as oil-derived thermo-plastics however as well as being 100% biodegradable PHA’s are biocompatible. To date, these plastics have been critical in the development of many medical procedures though traditionally expensive to produce.

The ASMARA platform marries two technologies a waste-to-energy plant and a bio-refinery at scale into one cookie-cutter project. The technology at the front of the process is Microbial Fermentation where a carbon-rich Hydrogen Producer Gas is forced into a tank of billions of microbes. This Microbial Fermentation process multiplies, fattens and then terminates the life of the microbes so they can be harvested to recreate a range of chemicals, fuels and materials that we use every day.

The waste-to-energy technology at the back end of the process converts solid waste streams into a Hydrogen producer’s Gas. A well demonstrated tried and tested thermo-chemical process which turns solids into gas in the absence of oxygen. There is no smoke because no burning occurs [because there is no oxygen] which is just as well because there is no smokestack or chimney for such emissions.

Hydrogen Producers Gas is created in a slightly negative pressure environment it is rich in hydrogen [H2] and carbon monoxide [CO] and these elements are suspended in nitrogen [N] together with lesser amounts of carbon dioxide [CO2] and a little methane [CH4].

The ASMARA Hydrogen Producers Gas to PHA process 

ASMARA like its cousin TITAN are platforms on which to convert abundant and or problematic organic waste into Hydrogen Producer Gas. Since we are converting waste into new materials the process is recycling however since we are producing far superior added-value materials we believe we are upcycling.

ASMARA converts problematic sorted Municipal Solid Waste [MSW] such as plastic together with household waste whilst TITAN convert abundant forest floor residues. Both platforms support different outcomes including [i] Combined Heat and Power [CHP] [ii] Gas to Liquid [GTL] tanking fuels via the fermentation of Polyhydroxyalkanoates [PHA] which produce ethanol or [iii] Bioplastics “nature-like” polymers which can be rolled to make films, extruded to make bottles and profiles or moulded to make components just like typical fossil fuel sourced thermo-plastics.